In Nepal, Cannabis has a long history of use both for medicinal purposes and as part of cultural traditions. Nepal’s climate and diverse ecology are well suited for cannabis cultivation. Nepal has a significant potential to become a major producer of cannabis and could achieve many benefits from its legalization. Farming, industry, and government will all benefit from cannabis legalization in Nepal. The economy and GDP will improve, tourism will be promoted, and the standard of living will be enhanced. All the possible downsides of legalization should be cataloged and considered, and reasonable steps should be followed to monitor the role of cannabis in Nepalese society. The global market for cannabis is expanding and Nepal can play a significant role in this sector.